Dr Daniel Stickler - Total Human Optimization

Full transcript: Dr Daniel Stickler on London Real

4:01 This is London Real, I am Brian Rose. My guest today is Dr. Daniel Stickler, the author, speaker, and medical pioneer in human optimization. You are a former vascular surgeon who performed nearly 3,000 operations before concluding that the traditional approach to medicine is not ideal for long-term health. Your work now focuses on longevity, epigenetics, and lifestyle optimization.

4:22 Today, you’re the medical director of the NeuroHacker Collective, a consultant for Google on epigenetics and AI in healthcare, and a lecturer at Stanford University, Dr. Stickler, welcome to London Real. Thank you. Great having you here. I’m super excited to talk about this stuff today.

4:38 We might as well tell everybody right now that you have been analyzing my DNA and hopefully you can share with me some of that knowledge today about how that might apply to my longevity and my fitness and all that stuff. Last year, I got a crazy challenge from a guest to run and Ironman 70.3 on 100% plant-based diet. I had no history with endurance sports. And I got stuck about midway and I had to call up our friend Dr. Tamsen.

5:08 She did blood work and found I was kind of low in B12 and I really needed her and the help to get through that race. So this stuff is important to me. I’m no spring chicken, I’m 48 years old. But I like getting everything out of my life. I was training breakdancing about an hour ago.

5:27 I swim every week, I do hand balancing, I still run distance, I still love being active, but I also love being the best me. And there’s a sign out in our world headquarters here that actually just went up, and it’s London Real, Transform Yourself. And I have these great guests in here, and we talk about ways people can transform themselves. I have an academy, we get people to build businesses and start podcasts. But thinking about your physical body is just as important when it comes to transforming yourself.

5:57 And so I’d really like to talk about that with you today. You know, this word epigenetics is a funny word and maybe you can help us define it. I had Dr. Bruce Lipton on here and he talked about epigenetics and it was one of our most popular episodes ever. And I think people find this fascinating that we kind of were told as kids that your DNA is this and here you go and that’s your life.

6:19 And then this concepts that you can express your genes in different ways, I think has a lot of people that are maybe hopeful. Also, I think mindset can have a lot to do with that. So maybe you could start off and just tell us, you know, what is epigenetics and why is it important? And maybe tell us a little bit about that. Yeah, I mean, we got to this point where we mapped the human genome and people expected these spectacular results that would come from mapping it, and it has been.

6:51 I mean, it’s the equivalent of the man walking on the moon. I mean, it’s spectacular that we’ve done that. But the interesting thing is that 99.5%, greater than 99.5% of our DNA is identical in every human being on Earth. I mean, you look at the three billion base pairs, the three billion data points that we have, and really less than a half a percent is what makes each of us different. And that less than a half a percent is what we call the polymorphisms.

7:19 But on top of that, we have the epigenetics. So the code itself doesn’t change over time. As we go through life, our code is identical. People ask me all the time, can you change your code? And you can’t.

7:32 It is your fixed code. It’s the hardware that everything operates on. The epigenetics is the software. And that’s where we actually have control over outcomes. And everything we do can change gene expression.

7:47 I mean, DNA is this unimaginably intelligent molecule. I mean, its whole role is for you and me to thrive and it’s constantly assessing environment and making changes in order to say, okay, this is a stressful environment. This is a good environment. What do I need to do to optimize my function in this environment? That’s epigenetics.

8:08 So when we eat certain foods, we call foods certain bioactives, we can change expressions of genes. When we exercise, we can change a third of our genome’s expression when we chronically exercise. We can change 2,200 genes out of out of 23,000. I mean fantastic depth of of Variability that is built in there and all we have to do is do the right things to make it happen Wow, that’s like that’s hard to believe that we could control our Genetic code like that with just practices. I mean you wouldn’t think meditation could change your gene expression Oh, yeah, but it can and most people don’t bother with any of that stuff really I mean a lot of people aren’t really concentrated on their diet on their movement or necessarily on their mindfulness They kind of just live out their lives and expect their DNA to get them wherever they’re supposed to go That’s not the way to live anymore. And that’s kind of why you stopped being the typical doctor and started doing this stuff, right?

9:07 Right. Yeah, the you know medicine has been based on this this premise and health in general I mean, it’s it’s all based on a premise of let’s have this stepwise postponement of death So you just go through life and you gradually deteriorate and we’re just trying to postpone that as much as we can that’s what medicine is about right now and When it looks at this human system that is us It’s looking at it in a very basic way. We are very complex systems. I mean everything we do changes expression we have unpredictability, we can’t be reduced into a reductionistic state based on an input and everything in medicine is based on that now and this is kind of defining us as a complicated system like a robot or an airplane or something like that, something where every piece of it can be analyzed and say if we put this input in we will get this output 100% of the time.

10:08 This is why we have algorithms in medicine and what we’ve been doing is creating a new paradigm around this where we look at the human system as complex and we take a complex system approach and everything is based on probability. So we are very data driven. We collect data. We get as much data on each individual as we can and then we say, okay, here’s where you are. How do we get you over here where you want to be?

10:34 And that’s the, people have this perceived limit of what’s possible for a human. What was it you said at the beginning, be your best you. What is your best you? Most people have lines drawn that, okay, this is my best me. We’re here to erase the lines.

10:52 I mean, the best you, with what we have now in advances in science and technology, we can take that version of the best you and move it well across that line now. And so you’re all about taking someone’s current state, looking at their genetics, their epigenetics, and saying, okay, what can we do to take you to the next level, as opposed to slowly dying. And then later, they’ll call you up in the old version of you at 65 and say, I need a bypass surgery, I got type two diabetes, and then we spend 90% of your healthcare costs in the last year of your life, and then we put you in the grave and we do it again.

11:29 75% of what kills us is lifestyle related. 75%, and what I’m talking about is the top 10 causes of death. Every one of them has an enormous lifestyle component, over 90%, you know, heart disease, cancer, and people say, well, cancer isn’t that a lot of genetics and things like, it’s not, it’s lifestyle. Cancer is lifestyle really. Yeah, I mean, you have a few that are very focused on genetics, but the bulk of the cancers are related to lifestyle in some way.

11:56 Eating, drinking, smoking, not movement, diet, and even stress levels. Absolutely, all of that, And even like accidental deaths, what’s the most common cause of accidental deaths? It’s drinking and driving. It’s sleep deprivation and driving. All of these things that can be prevented from lifestyle components.

12:17 And this gets me on this kick of preventative medicine. It’s such a poor term. I mean, everything about lifestyle is preventative medicine. So I don’t know why we have siloed it to say, Oh, well, we’re gonna take you into this preventative protocol for heart disease. Well, how is that any different than a preventative protocol for diabetes or preventative protocol for obesity?

12:42 Just means get the human system into a healthy lifestyle that translates into a positive outcome. And before we jump into like some of my results, what are some of the things that people should know they should be doing now to prolong their life, give themself a higher quality of life, And then also, how does knowing your genetic or epigenetic breakdown change those decisions? Well, the main thing is you can’t kind of take individual paths to wellness and think, okay, well, if I start sleeping eight hours a night, or if I start eating a good diet, when people want to lose weight, it’s like, okay, I’ll need the diet and exercise.

13:22 And yet, if they’re sleeping five hours a night, it doesn’t matter how good they are at that, it’s not gonna happen. So when we look at addressing something, we address the entire system, sleep, stress, nutrition, supplementation, hormones, cognitive function, movement, and environmental exposures. That is our baseline. You’ve gotta bring that into homeostasis, so all of those into a healthy level for the human system to really be primed to go to the next level.

13:51 And most people don’t do that. They will focus on diet and exercise or they’ll focus on sleep and neglect something else. And what we do is we focus them in on that. And it doesn’t matter if you come with MS or diabetes or you’re a professional athlete. This is a spectrum moving one direction.

14:08 You can enter it at any point. If you’re coming in and saying I wanna lose weight, you’ve got an end point. You’re starting here and you wanna end here. And then what? Nothing else left up here.

14:19 And this is where medicine is right now. You’re either diseased or non-diseased. If you’re non-diseased, they really don’t have anything other than preventative medicine for you. And it’s just the wrong approach, I think. Yeah, it’s like, okay, when you get sick or get something, you go to the hospital, they fix you and then they send you back home and wait till that other thing happens.

14:38 I’ve had people that have been to the hospital recovering from a heart surgery and the meal they give them is like something that, get them ill again. I mean, it’s almost a weird disconnect at the hospital. Whereas, okay, if it’s chronic, here, here, otherwise you go back into the system that creates these ailments. That must be kind of a weird, frustrating thing to be a part of as a doctor. I mean, especially since a lot of lifestyle recommendations are based on lobbying organizations and things like that, so it’s not really based on the true science of what we see.

15:09 Like what the milk lobby or the beef lobby or whatever it is. Sugar lobby. Okay, right. And even the medical profession is oftentimes controlled by companies that are looking for studies and the pharmaceutical company kind of own. even in research, it’s hard to get research that isn’t related in some way to a pharmaceutical outcome because that’s where the funding’s coming from.

15:30 Great deal that funding comes from the pharmaceutical companies and you’re publishing data that’s against the pharmaceutical companies, you’re probably not gonna get funding. It’s a really weird, scary racket and we’ve had a few guests talk about it, whereas if you wanna become a professor or a doctor that’s recognized, you have to publish. In order to publish, you have to have a study. The studies are funded by the pharmaceutical industry. They only wanna study things that are good for their drugs and it’s this kind of secret or open secret where this thing happens and yet we look at our doctors as kind of these greatest marks of society and they are, you are, but it’s all kind of tainted, right?

16:06 No, it is and I was talking with one of your staff members before we came on and we were talking about my typical day and I wake up at five a.m. And for the first two hours of my day, I’m on the internet, and I’m on there reading all the current findings, all the stuff that’s making headlines in the medical world, all the new research papers that are coming out. But for two hours, seven days a week, every morning, that’s what I’m doing. And for me, that just barely keeps me up with what’s happening right now.

16:41 You know, I look at it and I’m thinking, how doctors that have delayed doing stuff like this, How do they keep up? Because this is exponentially growing. I mean, I’m at a point where two hours may not even be enough to keep up anymore. And it’s just a wonderful time to be practicing medicine, for sure. Because all this new stuff and the biologics and the genetics and epigenetics, I mean, it’s just fascinating stuff.

17:10 And you’re big into longevity. You just came from a conference, I think, in Liechtenstein. And there was a great lecture where you showed, it’s online, and you showed two Mustangs, and one is from like the 60s, and I used to have a 68 Mustang, so this means something to me, and one is kind of this old junker that you might see on the side of the road, and one is one in this pristine condition, looks like mint from the factory. And you said, what if, when you were given your body, you said, this is the car, you have to have the rest of your life.

17:38 How would you treat it? Because with cars, we don’t think we’re gonna have it very long, we treat it this way, but it was just a great analogy that, especially when you’re young, you treat your body in a horrible way. And I have a whole history that came out with my movie Iron Mind about how I nearly killed myself with my lifestyle decisions. But it really is a vehicle that you need to take care of. And we can live long.

18:00 And not only long, we can live great long lives, right? You believe that. Right, I think, you know, health span is important. Health span, not lifespan. Right.

18:09 Because I see people in their 90s and I don’t see many 90 year olds that I’d wanna switch places with these days. because a lot of them are physically, mentally having issues. So I always think, why would I want to live to 150 if it doesn’t look great at 100? So you were saying. Well, I mean, my mother is 73 years old and she does crossfit, she does pull ups.

18:32 She deadlifted 165 pounds. She’s five foot tall and about 110 pounds. And she’s a beast. I mean, she can back squat 130 pounds and you just don’t see that in many people that age. And we’ve taken age and age has become a chronologic thing.

18:56 So, oh, you should retire at 65 and all. But you look across the population and chronologic number means absolutely nothing anymore. And we talked about this at this longevity round table that when does aging start? And aging actually starts preconception. So what happens in preparation for that child to be conceived can actually have a huge impact on that child’s life.

19:22 Then the intrauterine development, you’ve got huge impacts there. And then the first two years of life are highly critical for setting the stage for the rest of the child’s life. And we run a preconception through pregnancy program and it’s amazing what people are unaware of when setting a child up for what they’re going to be. Preconceptions, so before even the egg hits the sperm, it’s the egg? Oh yeah, really.

19:48 Guys don’t realize what their contribution is, but for three months, it takes three months for sperm to truly mature in the reproductive system. And during that time, that sperm’s not carrying just that little single strand of DNA. That sperm is collecting microRNAs, And microRNAs are like these little email packets that are being sent out through the body. So cells will say, oh wow, this is a really stressful environment, I’m gonna send a message out to everybody to tell them so that they can make adjustments to thrive in this environment.

20:20 So a male who is really stressed leading up to the pregnancy will end up with a child that can potentially have abnormal stress responses. An alcoholic father, they’ve actually shown this in the studies that an alcoholic father can actually contribute to having a child with fetal alcohol syndrome, even though the mother doesn’t drink alcohol. Wow. I mean, it’s amazing the impacts that we haven’t given credit to the fathers in their preparation for pregnancies.

20:52 Yeah, because, you know, I just thought it was DNA, that’s it, but it’s not, right? Because the synthesizing of that new baby’s DNA has all of these other contributing factors. Yeah, these microRNAs tell the DNA how to express. Wow. So they’re like, okay, stressful environment.

21:09 You need to change the way you’re functioning here. We’re gonna up-regulate this, down-regulate that. And microRNAs are becoming, it’s another realm of the biologics of exosomes. This is gonna be a game changer. I mean, right now we’re dealing with peptides, which peptides are turning the pharmaceutical world on its ear as these are coming into the market.

21:31 They’re not legal in the UK right now, but they’re prescription in Australia and the US. And we’re seeing outstanding outcomes with all the biologics. I mean, stem cells, we’re still not sure of right now. Peptides, we’re seeing amazing results. And the exosomes are the next thing with the microRNAs.

21:50 This is where we’re gonna start getting into true, I think, age reversal. Age reversal, absolutely. This is exciting stuff. And I love this whole human optimization piece. And again, like, I need to be at my best every day in order to do what I wanna do.

22:06 And I realize every day is precious for me. And so I’m always looking to that stuff. I mean, Dr. Tamsen had me on an IV bag a couple weeks ago. I’m not sure what was in there, but I’m trying that.

22:17 You know, I’ve played with nootropics in the past. Obviously, I did some B12 supplementation. I’m constantly looking to see what can be done. I’ve heard about peptides. I mean, it’s exciting.

22:27 And it can really make a difference in your consciousness, your output, and your longevity. Everything, I mean, you gotta look at this human system. I mean, this is your vehicle of consciousness. Everything in life is about experiences, okay? How do you want to experience life?

22:46 Do you want a Ferrari? Do you want it to be experiencing life inadvertently? You know, whatever it is you want to experience, you’ve gotta get this vehicle in that kind of condition. and we have the ability to do that. And then, you know, you don’t wanna have a little clunker that’s going along to experience life.

23:04 And so for us, I mean, we deal with clients that they want the Ferrari, they want the Bentley or the Mercedes. They want that vehicle to experience life in. Yeah, well, why wouldn’t you, you know? I mean, most of the people that watch my program are looking for new ways of thinking, are looking to transform themselves in some way, you know, with a meditation practice or a new way of looking at life, or a gratitude practice, or start this, but what about your own body?

23:31 A lot of times, okay, maybe there’s a diet and a movement practice, but they haven’t thought beyond that. And you’re talking about like eight different factors that you’re trying to optimize. And if one of them is off, you’re saying it can be kind of pointless. If your sleep is off or this is off. I gave a talk in Silicon Valley to a bunch of young tech entrepreneurs and they’re all looking for the limitless pill.

23:55 This is the movie with Bradley Cooper, where he takes the pill and he’s super smart. And I said, let’s start off with the fact that the limitless pill doesn’t exist, and it will not exist. There is no such thing as the limitless pill. Now, can we potentially get to where he was? Absolutely we can.

24:09 But I said, let me ask you this, how many of you in this room sleep more than six hours of night on average? And like two people raise their hand. And I said, you know what? I wouldn’t even consider working with any of you to enhance your cognitive performance until you’ve got your sleep straight down. They were shocked by that.

24:31 Because it’s like trying to get a clunker to run fast. They have to have those basics in place. I call it putting nitrous on a Pinto. You can hook it up and get one good run out of it, but after that, the engine’s trashed. I mean, that’s what happens when these young guys or girls that really don’t pay attention to the basic lifestyle components try to enhance in certain ways, and the system falls apart when it’s pushed that hard.

24:59 Okay, so there’s no magic pill. You really have to put in the work, but do the smart work, and make sure you’re monitoring everything. And after we met a few months ago, you were wearing your Garmin, and you’re like, I wear this all the time. It’s right there. That’s there.

25:11 And I started wearing mine to sleep at night, and I started tracking all my REM sleep and everything that you told me about, and it was really eye-opening. And again, what gets measured gets improved, So I was watching it and I was getting to bed earlier and I was seeing all these things. So that’s just one component of what you do. But first you look at the genetic analysis and then you take people through various programs. Some are medium level and some are super high performance.

25:36 Right, so our data collection is labs, genetics, epigenetics, we look at urinary metabolites, We look at cognitive performance tests. We look at lifestyle evaluations, quality of life inventories. So we run all of this before clients even come in. And we have all this data and we white board them. So we throw it up on a white board and say, okay, we’ve got five clinicians in the room and we basically are your board of directors for you.

26:08 And we go through it and we say, here’s where they are, here’s where they wanna be, or here’s where they can be. How do we get them from here to here? And then the client comes in to our practice and over a two day period, they go through brainwave mapping. So we do QEG brainwave mapping and we map for performance. I mean, I can tell you your brain will not be normal on a brainwave map and nor do you want it to be because high performers don’t have normal brainwave patterns.

26:35 And when we’re comparing to a normative database, if you’re normal, I would not like to have that happen. I wanna be better than normal. And so we look at that and we look at ways So we can enhance that. And you track my EEG while you’re having me do things? No, the EEG we look at is in a baseline state of eyes open and eyes closed.

26:55 What you’re thinking of is the psychophysiologic stress profile or performance profile where we hook you up to that machine that looks like a lie detector and we take you through five stressors and we see what happens to your autonomic nervous system in these stressors and how quickly they get back to baseline after it’s removed. So we see people like David Goggins would be very strong on this. We see like Google executives that are very strong on this where they can elevate their stress response and then bring it straight back down to baseline as soon as that stressor’s removed.

27:26 And that’s what high performance people do. That is. And it can be trained. It’s not something you have to be born with. So we look at that.

27:34 We look at human movement. So we look at your posture, your gait, your foot strike. We run electrical signals through all your muscle groups to find out if they’re working the right way. And then at the end of the two days, we sit down with you for another three hours and say, okay, how do we get there? Let’s map it out.

27:50 And then monitor you on an ongoing basis with the wearables and follow-up labs. And throughout the year, it’s just a stepwise progression. So not progression towards death, but progression towards optimization. You’re going up the stairs, not down when you come to see us. Right.

28:05 And so you’re making someone limitless, maybe. Without the pill? Yeah, all right, and reversing the aging process is what you’re trying to do. Yeah, I mean, what we’re looking at is we’re extending health span, that’s our ultimate goal. As a consequence of that, we’re hoping that we’ll also translate into extended longevity, which we’re working towards, but new technology is coming very rapidly and we’re already seeing things like Metformin, like Rapamycin, GDF11, all these new things that are coming on that are showing, Yeah, definitely a positive impact on aging.

28:40 We’ve got new analytics that are about to hit the market. NAD, all these things that can potentially mitigate the aging effect, but then we start moving into reversal. And it’s not gonna come all at once. I mean, we’re not gonna go Benjamin Button it. We’re gonna, we’ll have something that will intervene that’ll maybe knock you back three years, okay?

29:01 And then you’ll age another year, and then something else will come along that’ll knock you back five years. And so it’s going to be a gradual forward-backward movement that will eventually net into negative. And a lot of people don’t believe that this is gonna happen but I’ve been running in this industry for quite a while and this is the first time I’ve seen the excitement from everybody in the industry around it. This is not one of those ones that yeah, and there’s a group of them that are like all on board.

29:31 I mean, there’s a lot of people actually on board with this. and so I think it’s truly coming. It’s like that critical mass that it’s actually finally happening now, not 10 years. A hundredth monkey, it’s happening. Yeah, a hundredth monkey.

29:42 And I mean, I will say that it’s an interesting world that you’re in and like, you know, Dr. Tamsen’s in and people like Ben Greenfield in. Once I look in, I realize that there’s like, it’s cool to be part of this club. It really is. Because it is, because like, you know, some of the stuff with the peptides and all this stuff, it’s like, wait a second, like this is really next level stuff.

30:03 I always feel like I know something that’s a secret that the public doesn’t know. I feel like I’m in the medical illuminati. And I feel like, wow, I’m in a special place because if it wasn’t for London Real, I wouldn’t know about this stuff. But I mean, this can literally be a game changer in what I do every day. How much I can do, how great I feel, which affects my relationships, my energy, everything.

30:23 And if you’re trying to win in life, which I think we all are, you might meet someone that says I’m not trying to win, but everybody wants to live a healthier and happier and more productive life. And in Silicon Valley, maybe it means they wanna get the IPO faster. But even a single mother of two in London wants to win, and she just wants to win in her own way, which means great energy, great health, a lot of time for her kids, and optimization, right? So this is for everybody.

30:50 You’d be surprised, though, the number of people who really don’t have that desire, that are happy where they are. They don’t wanna put the effort into Creating a better outcome necessarily is also because maybe they were raised in a society where it’s not talked about where you get To end of life and then these things happen, you know stay calm and carry on I mean, it’s you know, this one this person’s worse than I am. So I’m okay It’s it’s changing a mindset of people to to understand that there are Really no limits to our potential and where can we go with this stuff?

31:28 And you know the biohackers and you know, a lot of people don’t like the term biohackers, but they they’re truly people that have pioneered a lot of this a lot of this self experimentation and let’s face it We’re in an end of one category this number of number of participants in the study is one and that’s you You know, we can’t keep comparing on population based Comparative levels and this is what all the studies are doing Those can provide probability outcomes for us, and we can look at those to guide us. But what I have seen in my medical career is that everybody responds in an individual way. I mean, what’s the perfect human diet?

32:07 There isn’t one. There is a perfect diet for you, typically, and it takes some trial and error to figure out where it is. The more data you have going into it, the shorter that time of trial and error can be. This is why we like the genetics in the lab work and getting all the data to kind of shortcut that process. But every individual has their own unique characteristics.

32:29 And even if you have this high probability that, oh, this is the perfect diet for you and we put you on it, we can see in the system, the system’s stressed or it’s not stressed. How’s it responding? We look at resting heart rates over the course of a month. We look at stress scores over the course of a month. We can correlate all this data.

32:48 I mean, you do something to intervene with your sleep patterns. We can see what’s happening with that. So wearable technology is, it’s not 100% accurate, but the dynamic of it is what’s important, is how is it changing based on the input that we’re putting into the system? Yeah, and it is very specific to the individual, and that’s what’s really interesting about it. Like you need to get a human opinion, because it’s all of these numbers, and you really have to have your team, like you said, your own board of directors, look at you and say, okay, This is what we think we’re gonna do for you, but we’re gonna monitor all of this stuff.

33:20 And over time, we’re gonna really optimize you to where you can have all of these things that you want, which is really interesting. So I’d love to jump into some of my results. So I did this DNA array, and so I spit into a tube and sent it off, and then you guys got all the numbers. So it’s a bit like 23 and me, but I found when I got 23 and me back, it just didn’t tell me anything. I was like, really, I got a gene that does this, but you look at things in a different way and then you have a team that also can take this information and then give you this entire optimized strategy.

33:53 And so, and if people are curious about this, by the way, then go to LondonReel.tv forward slash health, where this whole system is there, where people wanna go ahead and take this test, and then you have total different performance levels that you take people on, right? You have, you have like- We have the full medical optimization and we have kind of lesser levels of that. And then we have our health coaches, which we have 300 health coaches worldwide that have trained in our model.

34:20 Done 90 hours of online training and they’re very skilled in the interpretation of the genetics. Right, so people get the test and then they get on with one of those professionals and they walk them through. And then there, it’s as far as people wanna go. If they want, they can go to the next level and get the whole Rolls-Royce performance level of this stuff. So anyways, I found this stuff fascinating.

34:41 So I’m not sure if I should ask, but what did you see from me? And how can that affect me going forward? Yeah, typically, we supplied you with a report and we typically will not give the report unless it’s being given through Coach. So the time when you get the report is while you’re on with the Coach. So you had a little bit of pre-read on it.

35:04 But looking at it, there were certain things that did show up. One of the things I found is that you carry a variant of APOE and that variant indicates that people who carry this variant are best off to number one exercise, not smoke, and minimize saturated fat in the diet. So if you’re eating a high saturated fat diet, there’s an increased probability of cognitive decline and development of atherosclerosis, these kind of things based on your ability to transport the saturated fats well with that gene variant.

35:37 So for me, my Achilles heel would be smoking, not moving in high saturated fats. And somebody next to me might be able to do those things and not be as in a bad spot. But for me, genetically, I’m predisposed to where. Like me, I’m better off on a higher fat, lower carb diet. And when I say higher fat, I’m not talking saturated fat.

35:58 So even in somebody that can do well with saturated fats, we still try to keep it less than 10%. And focus on the other fats, the monounsaturated fats, the olive oils, the avocados, and the omega-3s, the fish oils. So even when people do well with total fats in general and saturated fats specifically, we still try to keep that at a minimum. But for you, less than 5% would be ideal. But you also have these variants in your carbohydrates that indicate that you do better with a higher complex carb diet.

36:31 So your plant-based diet was actually very good for that. Now, I can’t say that I have many performance athletes that can get away with a plant-based diet and you probably had a little bit of reserve from going into it with the other aspects, but this gene, gene variants that you carry, people tend to lose abdominal fat better with a higher complex carb. This isn’t talking about like sweets and simple sugars and simple carbs, this is complex carbs, so over 200, 250 grams a day of complex carbs, which could be like what, a bread or a rice or?

37:12 Vegetables, and I count the starchy carbs in there, so the sweet potatoes, the rice, those tend to contribute to that, but you don’t want that as a predominant starch as part of the carbohydrates. Okay. But it’s the one that we say these people burn fat in the flame of a carbohydrate. So they’re the ones that will go on the ketogenic diet or the paleo diet and they’ll be like, I’m gaining weight and all my friends they’re losing weight on this diet, and we’re like, well, try adding some more complex carbs in there.

37:42 All of a sudden, they do that, and they’re losing weight, and their friends are jealous because they’re able to eat the complex carbs and get good results. Interesting. And yet, we kind of, as a society, have this one-size-fits-all, buy the paleo book, buy the keto book, and it’ll work for you. Right. But without knowing your genetic component, you could set yourself up for failure.

37:58 Well, see, dietary-wise, we, ancestrally, our genes adapt, not only in the inherited polymorphisms that we have, but also in gene expressions that we carry through generations. So somebody that comes from an Inuit Eskimo family that’s been there for generations, they’re gonna thrive on high fat. Their genes are adapted to that environment. So they can eat the high fat diets and do exceptionally well with it. They won’t get heart disease.

38:26 They can even eat really high saturated fat and get away with it. Somebody from Southeast Asia though, who background wise is more on the starchy carb dietary patterns, their genes have adapted over centuries of evolutionary development to say, we’re gonna thrive in this environment because this is the environment we’ve been exposed to. And then trying to put them on a high saturated fat diet, they’re gonna get the heart disease. So in the US and in Europe, we have such a hodgepodge of ancestry that without having our genetics, we just have to guess at what’s happening in that.

39:07 And by looking at that mix of what we have in the genes, we can actually adapt to a, or we can identify a dietary pattern that’s going to predict the best outcome. Now, given that, most people of European ancestry do really well with Mediterranean-based diets, and it’s pretty consistent in the genetics. So, you know, if you have to guess without getting the genetics, a Mediterranean-based diet is a very healthy way to go. Which means olive oils, fish, vegetables, period.

39:42 Period, yeah. Stop there. Some grains, a little bit of grains, but not much. Okay, yeah. All right, and that’s your just general start point with a lot of people of the European descent.

39:51 Yeah. Okay. Now with my gene, it shows that maybe some complex carbs might actually help me. Right, okay. And then I’m predisposed that if I am exercising Regularly and then not smoking. Yeah. Okay. Well, I stopped smoking years ago. So that’s good And I do exercise every day because for me it just it gets me to my optimal level like well And you’re you’re exercise genetics and we do a pretty deep dive in exercise genetics I mean our total report of everything you got is about 80 pages long. Yeah, it’s massive and Your exercise genetics are exceptional and it doesn’t surprise me. I was a science geek in school. It doesn’t matter I mean, you’re carrying them when you start using them you’re activating them So it just makes it easier for you to train in these I mean, I’ve seen people that had endurance genes that became Olympic sprinters and it doesn’t Prevent you from doing that. You just have to work a little harder. Okay doing it But you have genetically gifted genetics that give you the ability your vo2 max genetics are exceptionally strong So if you sit on a couch, it doesn’t matter because you’re not using them You’re not training them, but because you have those if you start training them, you will train easier you have genetics for Muscle for Increasing strength to exceptional levels without creating a great deal of hypertrophy in doing so So you don’t have to get large to get the strength? Okay that you have

41:18 You have recovery genes that tell us you can go back-to-back days on intense workouts and probably keep the inflammation at a minimum I would still track based on your on your metrics on the garment and how your stress level does with it Which be tracking my head resting heart rate to track that mostly or well, it’s it’s based on first beat technology algorithms and Most of it’s about the PPG heart rate Analysis the ongoing daily analysis. So when you exercise you should see a high stress peak, you know I had clients that that said, you know But you told me to watch things that cause high stress and when I exercise, I get really high stress and they’re like, should I not be doing as that intensive? I’m like, no, no, that’s really good.

42:03 You just gotta look at how fast it gets back to baseline. If your stress stays up through the night after an intense workout, then you probably shouldn’t be doing another one the next day. But if you quickly get back to baseline stress levels, then it’s perfect because stress is what creates positive outcomes for us. I mean, people think stress is a bad thing and stress is really what contributes to longevity and healthy longevity. Gotta have some.

42:31 Yeah, you gotta have it, right? Otherwise. Think about this, I mean, exercise in and of itself. You know, ask a physician, why is exercise healthy? Creates more free radicals than anything else that we do in the course of a day.

42:44 It tears muscle, it traumatizes joints, you get micro tears and hemorrhages and everything else, how in the world is this a healthy thing to be doing? And the answer is, it’s because of the epigenetics. Because that stressor on the system tells the system, this is an unfamiliar environment. I have stressed the body, so I need to make adaptations to thrive in this new way of living. And this is why when people go on a weight loss program, you know, they’re couch potatoes And they decide oh, I’m gonna go eat. Well and exercise and they do it for three months. They lose 20 pounds and They’re on on cloud nine and then the next three months they do the exact same thing And there’s no weight loss and they’re like, okay what happened?

43:33 Well, what happened is they’re familiar zone of where their body’s functioning Shifted up So they’re down here at the beginning and they’re exercising. They’re going out of the familiar zone in distress The body says, whoa, this is not my familiar zone. I’ve got to change gene expressions to get myself into this new zone. And once it fully adapts, you can continue doing that, but if you’re not pushing it a little bit harder, you’re not gonna get those results.

43:59 Gotcha, gotcha. All right, so interesting what you’re saying about me, because when I did the Ironman last year, I was training like a lot, like probably like 14 different workouts per week, you know, because the back-to-backs and all that stuff, but I was recovering really well. I mean, I was training every day for 80 or 90 days and I was able to do that, so that was interesting. My VO2 max would mean, what, is that good for a kind of sprinting anaerobic cardio or is it good for endurance as well?

44:28 Both, VO2 max, I mean, you know, Lance Armstrong had one of the most exceptional VO2 maxes and you know, you can attribute it all you want to performance enhancement stuff, but it wasn’t that. He was not, he was genetically gifted with a VO2 Max that was exceptional. And so that gives him that ability to do those kind of sports and excel in those. VO2 Max is much better for a more endurance type sport like the Ironman or Marathons or something like that. But it also can give you benefit in the short term sprints, but not as much.

45:04 VO2 Max is more aligned with endurance performance. But then when we looked at your, you know, in all of our genes, what we do is we look at a, in the athletic performance, we do something a little different because what we do is we compare them to elite athletes. So we have, I think we have 110 different gene variants that we’re looking at in athletic performance. And we compare them to, okay, this is your comparison to elite endurance athletes. This is your comparison to elite athletes with high VO2 maxes.

45:35 This is how you compare to athletes in the strength world. And what we found with you is that even though you have really strong endurance genes, you’re actually even better in strength and power. So your power, your ability to train in power sports is higher. So you can look at that and say, well, you know, mixed sports, you would do really well in two. So like soccer or basketball or something like that, that involves a combination of things, You know jujitsu, okay, those kind of things you’re gonna perform well because it requires both strength and endurance Interesting and now that’s what I was always drawn to in the past I mean once I stopped being a science geek and I had no sports training But I was always drawn to that kind of anaerobic cardio stuff, you know Which usually was martial arts and then that kind of thing and I guess I knew I could do that So the endurance was new to me But it’s interesting you say that because that’s the stuff that I do feel like I can do with a hand balancing in the break dancing lately and that kind of gymnastic type stuff.

46:39 So that’s helpful. What’s the bad news when it comes to my evidence? There is no bad news because everything we look at is things that we can take action on. We don’t look at it. We’re not going to tell you, oh, well, you’ve got this risk of breast cancer or whatever it is.

46:55 We don’t look at things like that. We look at everything it has to do with things that we have control over, that we can change the outcomes. One of the things that we did notice is in your mercury processing genetics, you do really well with inorganic mercury. So this is the mercury we get from pollution, from mercury amalgams, things like that. But with organic mercury, you don’t process it quite as well, probability-wise, based on your genetics.

47:25 The interesting thing is that your body response to mercury is also not very good. So now we’ve talked about putting on a high fish diet and now we’re talking about mercury. So this is where we have to correlate these things. There’s a lot of myths about the mercury in fish and what you want to look at when you’re looking at fish is the molar ratio of mercury to selenium because selenium will bind up the mercury and almost every fish that we typically eat is really good.

47:58 The studies that were done on the pregnant women and the fish consumption, they were We’re actually done up here on Faroe Island off the northern coast of Ireland. Where the predominant fish that they eat is pilot whale. Pilot whale’s one of the only fish whose molar ratio of mercury to selenium is much higher in mercury than selenium. All the other fish, a complete reversal of that process. So don’t eat shark, blue marlin, and pilot whale.

48:27 And in pilot whale The rest of the fish you’ll do fine with should be okay But you can also supplement with things like NAC or you can supplement with a little bit of extra selenium when you’re consuming Fish meals. I mean, that’s fine, too. Okay. Good. No, I had some hair analysis done last year And I was I was eating a lot of sushi before I went Plant-based and that definitely that came up the mercury levels came up in mine It was like noticeable, but it was also like ratios like you were saying but So that makes sense, what you’re saying.

49:00 And mine were kind of high. And then once I actually stopped eating the fish when I went on a plant-based diet, they did drop way down. So there was definitely something there. Well, they’re still gonna be looking at recent intake on that. So if you haven’t been eating things with mercury in them, your mercury levels will drop dramatically in the blood testing, the hair testing, the urine testing that’s done.

49:21 Okay, and earlier you’re saying like, but if I was smoking, I probably am more susceptible to dangers of smoking. And if I am eating saturated fats, that could be more dangerous to me. So that’s something I do need to look out for. Yeah, okay. It’s interesting because I have a family history of heart disease.

49:38 My grandpa was a rancher in Arizona and looking back, I mean, it was all about a lot of saturated fats, a lot of eggs being fried in bacon, fat, oil. Oh yeah. And my grandpa and my grandmother both died from heart-related diseases. And I don’t know if that’s something in my genetics or not, But it’s something that if they had had this information and all these ideas, I mean, it literally could have saved their life. Yeah, one of our children is, we fed him bacon like every day for breakfast all through high school.

50:11 He came back with a variant like yours with the A-Pole. We’re like, oh, what do we do? We should have had this sooner. But you deal with what you dealt. And it’s rarely ever too late to do anything about it.

50:26 That’s the cool thing. Okay. Right, because wherever you’re starting, you’re starting there. Right. It’s like this is the first day of the rest of your life.

50:32 Exactly. Or there’s another analogy. They say when’s the best time to plant a tree 20 years ago or today. Right. So now is the time.

50:39 Make the quality of your life good now. And look, I mean, I can argue to that. I mean, you know, I beat my body up for so many years. I abused it with alcohol and drugs and all that stuff. I wasn’t moving on a regular basis.

50:51 And now I’m not doing all that stupid stuff anymore. and I’m training every day, and I feel great. Like, and I went through the same process a different way between medical school and surgical residency and then 10 years of being a surgeon. I mean, my sleep was disastrous. My diet was horrible.

51:14 The only thing I did right was I exercised during that time. So I didn’t get overweight, but I wasn’t in good shape. And then after 10 years of surgery, I actually got a telomere test that kind of opened my eyes. I was 10 years older by physiologic age, by telomeres than my chronologic age. Wow.

51:33 And I was like, what have I done to myself over these 20 years of life that were so impactful to do that? I mean, when I went into medical school, people joked and called me Doogie Houser because I look so young. Then I realized when, you know, here after 10 years of surgery, I look significantly older than my age. And then my telomeres confirmed it, and I was like, okay, I’ve got to do something about this. So it’s not too late.

52:01 And what did you start doing? At that point, I really got myself on an optimization program and dove full bore into learning how to do this. I’d been dabbling in it a little bit up until that point, but this is where I really pushed it. I became the end of one. I would test everything, I would measure everything, And I would make changes based on what I saw changing in the system.

52:24 And that has made a huge difference for me. Just now I feel like I’m in better shape now than when I was 20 years old. Wow, what’s a telomere? So people know. We’ve had Dr. Joseph Benz on here and he’s talked about telomeres and I know a little bit about them but I don’t know enough.

52:40 So what are they? Telomeres are these little tiny tails on the ends of our DNA. And every time our DNA divides, it shortens a little bit. And every different cell type in the body has different lengths of the telomeres. But once you fully deplete those telomeres, the cells become senescent.

52:57 They can no longer divide. So they’re not going to create new generations of cells. And they also quit functioning optimally. And they become senescent cells. There’s like these zombie cells that sit in our body that take up nutrients and secrete toxins.

53:13 That’s why, at the beginning, We talked about a new breed of medication called cenolytics that go in and actually eliminate these cells Which is really cool thing that we’re hoping to do But we’ve also got to figure out how to add telomeres to to this and there’s some pretty good gene research on Gene insertions and they’ve actually been done in humans that have increased telomere length that starts to get really interesting. Yeah There’s this Hayflick limit. Is that kind of yeah The Hayflick limit is where you’ve shortened them to the point where they can no longer divide Okay, and that the length of your telomeres is a good indication of Kind of your yeah, there’s there’s a couple ways to test that I mean a lot of people will look at the average length of telomeres when they get tested We use a company out of Spain That looks at the shortest percentage of telomeres I I heard it said one time if you’re in a room full of dynamite do you want to know the average length of the fuses or the shortest fuses and And the shortest fuses are the ones that are going to potentially put you at risk for chronic disease cancers those kind of things Okay. All right. So you watch those numbers? Yeah, I I’ve been leaning more towards epigenetic age looking at methylation patterns on the DNA To look at what a person’s age is because that changes more quickly so we measure that in all of our clients and then we will check it at six months and

54:33 We’ll actually see reverse aging occurring by the methylation patterns on the DNA Wow This must be big in Silicon Valley where people are talking about uploading their consciousness to the cloud and all that You know, it’s weird because that group tends to be so focused on the consciousness aspect that they ignore the body Really? We find that quite a bit in in that group is that they all want the limitless pill They all want you know to experience plant medicine They all want to alter their consciousness and expand their consciousness and everything and they’re missing the experience of life as it is and they ignore the body. I ended up getting them after they’ve kind of come to that conclusion.

55:15 When something breaks. Yeah, but really, who’s really adopting this? The business executives, the entrepreneurs, the athletes, the special force of soldiers. These are the people who have been so into the interception of the body and everything like that that they’re looking to take it to new levels. They have that forward-facing kind of mindset that opens them up to what’s possible.

55:44 Yeah, we were talking about this earlier about how Ironman, we were talking about how the average income of an Ironman competitor is really high. $250,000, the average Ironman competitor. It’s $250,000 annual income. And what does that tell you? It is the basic mindset of that individual.

56:04 They are driven, they are data-driven too. So they look at data, they respond to data, they set KPIs, they have the tenacity to stick with things. They are focused on making things happen. This is the whole mindset of health optimization. It’s the same mindset of business.

56:28 To train for an Ironman competition is no different than starting up a company. It is that same mindset that drives both. It’s interesting, isn’t it? It’s like having the vision and knowing you have to put the work in every single day. You’ve got to get uncomfortable.

56:43 You’ve got to be data-driven. You’ve got to see the feedback. And yeah, and probably always get yourself into this uncomfortable array. Because once you have a success in business, you can’t coast on that. There’s no growth in the comfort zone.

56:57 Right, yeah, in business or in life. Interesting, all right, so this whole system that you do and that we’re talking about right now is really for high performance people or people who really want to. We have entries across the board. I mean, the Appearon Zoi Corporation, and Appearon actually means limitless. That’s the name of our company, Appearon, and Zoi means life, so limitless life.

57:21 We encompass a full spectrum, so we have the high-end medical pieces for people that want to really enhance it at levels just above and beyond. We have more baseline medical interventions and then we have coaches that are out there that are non-medical but they understand the lifestyle pieces and they can give guidance to people in that realm and help them move forward in that. So you can range anywhere from an investment of $400 up to $60,000 but it’s wide open for people across the board.

57:58 For people across the board. So if they wanna get a baseline of where they’re at and find out a lot of these genetic and epigenetic factors and get that consultancy call to give people, they can do that for, it’s actually quite a low price, right? Yeah, I mean, normally it’s 6.97, but for your viewers, we’re doing the 3.97 program where they get a full hour with an epigenetic coach and an interpretation of their genetic data and their genetic test. Okay, and that’s all at londonreal.tv forward slash health.

58:25 Now, if they wanna go to the next level or say I wanna go to the next level, what are some of the things that we might do with me next? You talk about these eight different components, but say I wanted to go all in. All in. What would you be doing with me over the next few months? Okay, first of all, we have to, we set a month date for your visit, and in the interim we get all the testing that we can get without you being physically present.

58:49 So we’re getting in blood work, we’re getting the epigenetic age test, we’re getting your genetics, we’re getting your online testing done, that we can collect that and we white board you before you even arrive. And then we have you come into the clinic, you spend two days with me or one of our clinicians and you will go through a battery of tests over a two-day period and you’ll spend generally about six hours one-on-one with either me or one of our clinicians and getting to know who you are, what drives you, what your goals are And then at the end of that second day, you walk away with a plan. You walk away with, this is how we’re gonna do it, or at least this is how we’re gonna start it.

59:33 And what is that next step? Well, that next step is gonna be decided at the one-month call. One-month call, we check in and say, okay, what’s working, what’s not working? What are you happy with? Is there next steps for you?

59:45 And progression through the year. And I creep on your data, too. So I get onto your Garmin dashboard And I’m looking, I’m going, hey, what’d you do the other night that you only got five hours of sleep? You know, look at this, your stress went up for two days after that. So let’s figure out what’s happening there.

1:00:04 We teach, using the wearable data, we’re able to teach interoception. Interoception is this understanding of how things affect the body. And like, we understand when we’re hungry, we understand when we have to have a bowel movement, or when we have to take a drink of water, when we have to sleep. But there’s other aspects of life that requires interception. And understanding these signals is one of the things that wearable technology has been able to get us to read that language or understand that language.

1:00:35 Yeah, and I wore one of those for the Ironman train last year and it was so powerful. My coach, Samantha Murphy, was in Missouri, I think. But like, you know, she was tracking everything. And it actually got me to go through the workouts because I knew she was watching me and as soon as I’d finished my half marathon on Saturday, I’d be like bam, and I’d send it to her and she’d give me a comment like minutes later, she could see my sleep. I mean, there’s so much information on there that it’s powerful, and especially if they’ve got someone like you watching that.

1:01:03 I mean, you can literally dial in what’s going on with them and that’s… And people don’t appreciate the benefits of a health coach. You know, I always tell people, I say, you know, I am not your cheerleader, I am not your mentor, I’m your coach. I’m the sherpa that’s helping you up Everest here. I can give you the advice but it’s up to you to really do the work and you give me feedback on this is good, this is not good.

1:01:30 But I’m also not going to be the one that’s sitting there cheering for you when you’re not doing what you need to do. I’m calling you out on your bullshit. There’s no questions that when you’re working with me and people pay a lot of money to work with me but they pay a lot of money to be yelled at sometimes and not necessarily yelled at but chastised over what they’re doing. Yeah, it’s funny how so many people probably would just ignore that part of their lives and yet they’re so obsessed with the money or I wanna feel good and then they wouldn’t even think about it.

1:02:02 People think they know this stuff though and this is, you know, it’s like me in business, you know, I’m not gonna do my own taxes. I could probably make an attempt at it but that’s not my area of expertise. People have an assumption that they’re good at health And some are, but most people still need guidance. I mean, you look at the professional athletes, they all have coaches. You know, these are people who are really tops in their game.

1:02:27 You would think that they would be able to read this stuff on their own, but they understand they’re not that objective observer that can look at things from that perspective and say, you know what, this isn’t working, or this is working, or let’s try this. And your typical client is like an entrepreneur, You know, are there, you said some special forces people. Is it just people who just wanna be the best? It is, and you know, I have people, you know, I have stay-at-home parents that work with me too.

1:03:00 So all we require is that you have a forward-focused mindset. You look at it and say, I understand that I’ve got self-imposed limits maybe, and I know that those limits are erasable. Those lines can be erased. That’s all we require, is the full understanding of, yeah, there’s potential, and I want to achieve it. You know, it’s the people that limit themselves and say, you know what, that’s not gonna happen.

1:03:30 I don’t wanna work with that kind of person. You have like a hierarchy that you talk about in some of your speeches, and I was wondering if you could kind of go through it with people, and you talk about, you know, kind of nutrition, fitness, and biomarkers, and then you go down into kind of like thyroid, testosterone, gut health, stress optimization. I wonder if you could just talk about that for people that are listening that are like, okay, I might go ahead with this epigenetics test, but still, what are some of the things that I’ll be doing that you think are really important?

1:03:58 You’ve been watching some very old videos. Yeah, okay, those are old, right, yeah, okay. So we have, we now have a four-tiered system. So we have the unbalanced state. Unbalanced state is where the lifestyle factors are not all in optimal states.

1:04:15 And you can have maybe six of the seven balanced, but if the seventh one isn’t there, you’re not in homeostasis. You’re an unbalanced state. And people can come in with MS, diabetes, high blood pressure, whatever it is, but you can also have the person without disease that comes in that’s just not optimized in lifestyle. So our first step is to get them into homeostasis. And the Greeks knew this.

1:04:38 I mean, the Greeks defined the, even the term dietetica was all about man’s way of living, how much he slept, his movement, his exercise, his job, his family life, his food. That was dietetica, and the Greeks knew that, and it was all about being in homeostasis. So how do we keep the system balanced? Once you’re there, there’s ways to leverage at that point lifestyle factors. So this is where epigenetics plays into it.

1:05:06 How do we enhance gene expressions? How do we suppress detrimental gene expressions? How do we create the next state through lifestyle? And this is what we call the optimized state. Once you’re optimized, that’s where the fun begins.

1:05:22 That’s where we go into the enhanced state. This is the state that generally is not achievable naturally. And this is a state that’s only been achievable in the current decades, because we didn’t have the ability to get there. Now through medications, peptides, technology, all this stuff we can bring ourselves into this enhanced human state. And it’s pretty cool.

1:05:49 It almost sounds like we shouldn’t be talking about it. It just almost sounds like kind of a secret, you know, that we could be these kind of optimized humans. Well, we were talking about Stephen Hawking’s last book that he wrote. And he was talking about genetic manipulations. And he said, we can make these laws to try to regulate this, but people are gonna go ahead and do it anyway.

1:06:10 And we’re gonna create a self-evolving human race that you either get on board with or you will become the slave of this new paradigm. And I think that’s a bit doomsday-ish. I don’t think it’s quite that. But I think we have to start looking at the fact that we are in a new evolutionary phase. and this evolutionary phase is the enhanced human.

1:06:35 How do we move things? People say, you know, when I give talks and I talk about enhancing cognitive function, I say, how many of you would be for increasing brain performance in a child through gene manipulation? And very few of them would be. They’re like, no, no, that’s a little creepy. I said, well, what if the child was gonna be born with a genetic defect, would you be okay with manipulating the genetics to avoid that defect?

1:07:06 And they’re like, oh yeah, that’d be okay. So 90% of the room’s okay with that. And I said, but think about this. How are we gonna solve world problems? We can solve world problems with a greater probability with more intelligent population if we drive things towards this.

1:07:26 And gene editing in this stuff is not expensive and it’s not gonna be exclusive. I mean, you can do it in a garage. I mean, it’s amazing how simple some of this stuff is. I don’t see it as going to be absolutely exclusive to a certain group of people, but it’s gonna come. And it’s gonna be trial and error, and some people are gonna have some bad outcomes with it at first.

1:07:47 But it is something that’s going to happen. And people say, well, you know, making people more intelligent isn’t gonna be the best thing to do. You look at Hitler, and you know, Like, but what if we could increase empathy? What if we could increase compassion too? I mean, why are we limiting ourselves to thinking that this is just the one thing by enhancing cognitive function that’s going to occur?

1:08:11 And, you know, I’m very optimistic about what’s coming, even though I hear a lot of people that are very scared. The thing is, is if you look at humans and technology over the last hundred years, this is coming, right? Like you said, it’s coming. And knowing the way we are as humans, we’re gonna optimize. And someone’s gonna raise their hand and say, yep, I want the gene-edited kid, and once that rabbit’s out of the bag, then everyone will want that.

1:08:40 And it’s weird, you know, with London Real, like we’re talking about ideas and mindsets and people trying to have a different way they look at the world and just doing basic practices like meditation and gratitude and affirmations and kind of hacking the brain and all that. I firmly believe that that will set you apart from other humans. So if you really want to be in this game You know this medical piece is is the next level and you can either get on board or not, but it’s going that way And if you’re not on then you really will be this Second-class citizen right and I feel like there’s a guest I have in here named David Eich and he says all sorts of crazy stuff But he says there’s a postage stamp mentality that goes on in the world where you’re told that that this is the way the world works and the Queen’s the authority in this country and you have to go to school and then you Have to get a job and then you have to pay for your pension and then you have to go to the doctor when you get cancer and then you die and it’s this limited mindset and it kind of creates this kind of slave class and then you got people that think outside the box and They take their brains to the next level and they start companies and then they’re over here So we already have this kind of class thing happening and it’s just gonna go more But I thought it was funny, I can remember reading that the people who graduate number

1:09:56 One in their class are the people that are usually highly successful and have good incomes and everything like that. But the people that change the world are the people that were in kind of that middle part of their class. They’re the ones that have that world-changing impact. And I think it comes down to that vision of what is possible. And that’s our goal.

1:10:22 Our goal with AppearOn is to fundamentally change the worldview of what’s possible and create that through. And we chose to do it through grassroots. Instead of going from the medical establishment down, we chose to do it through the coaching model. So we have our own medical program. And now with our coaches, we’ve got 300 coaches worldwide, adding 10 to 20 new ones a month, and 30% of them are physicians looking for something different.

1:10:54 And the bottom line is everybody joining wants to change the world in some way. They want a better program than what’s available right now. What are some of these substances that you’ve kind of been talking about that have the peptides, the exosomes, the stem cells, Like this kind of next level Illuminati type stuff. This is cool stuff. This is what I call the biologics.

1:11:19 So biologics are interesting because biologics are, they’re familiar to our body. Our human system knows what a biologic is. It recognizes it and says, oh, okay, I’ve seen this. So like a peptide is typically they’ve taken a protein or a peptide that the body already makes and taking pieces of it. and introducing it back into the body because each protein, proteins are what we call pleiotropics.

1:11:47 So think of it like this, there’s a ring full of keys. So let’s take the growth hormone protein as an example. It’s got all these keys on it and every different cell type in the body, whether it’s a fat cell, muscle cell, bone cell, brain cell, they all have different locks. And so we can take that protein now, like growth hormone protein and start extracting the keys. And then we can inject those keys to affect the one area without affecting the other areas.

1:12:22 I mean, this is highly specific interventions that are being achieved with peptides. And the body responds to peptides. So when the body’s familiar with it, it knows how to respond to it rather than react to it. medications and nutraceuticals, even all these supplements that we take, it’s a body reacting to something. And we have to deal with off-target effects.

1:12:47 So even though we have this positive effect here, we’ve got to deal with these other side effects over here that is affecting these processes. With responding, we can get very laser focused in interventions. I mean, we’ve got peptides that will repair the body in ways that is just exceptional. I mean, cartilage regrowth, wound healing gut healing Peptides we’ve got cognitive enhancement peptides I mean pretty significant cognitive enhancement peptides We’re getting some impressive results when we do cognitive functional cognitive testing when we use these That’s small on your face. This scares me You really my refrigerator probably has more peptides and that’s food. So, you know, I I try them out for sure and you know the the depth of what we can achieve in the human system is open to a whole new world.

1:13:43 I mean, there’s 60 FDA approved peptides in the US right now and there’s like 7,000 known peptides. And we’ve got new treatments of cancer that are coming out in the peptide realm. We just had a peptide approved this week that was, it’s PT-141, which is enhancing female sexual response. but it just got an FDA approval for a pharmaceutical company, which surprised me, because PT-141’s been around for many years, and now it’s been patented as a pharmaceutical.

1:14:18 Wow, so super exciting peptides. What are these other things, what are exosomes? Okay, so exosomes are these micro-RNAs, so these little packets of emails that I was talking about being sent around the body. With the exosomes, or with the micro-RNAs, where we’re seeing these, they’re short little segments of RNA that go in and tell the cells what’s happening and what to do. One of the things we’re finding is that like in parabiosis where we hook an old rat circulation with the young rats and it rejuvenates the old rat, a lot of that’s coming down to the micro RNAs that are secreted.

1:14:56 So over time, our DNA is programmed to age and die. I mean, that’s what it does to our bodies is it’s truly programmed for us to go through this process. And it changes certain things like these micro RNAs that are being expressed. So you can take the micro RNAs from a young, young being, inject them into an older being and you see rejuvenation capabilities. Now we can start looking at how do we sequence these micro RNAs, encapsulate them into exosomes and then get them into the human system.

1:15:26 Wow, speaking of old rats and new rats, How long do you think I should expect to live? Depends on who you talk to. I’m optimistic about the potential for it, and what we’re gonna see is not that not that you’re gonna all of a sudden reverse age, it’s just not gonna work that way. What we’ll do is we’ll find interventions like Synalytics that may set the clock back three to five years. And then you’ll age a year or two, and then something new will come along, like something to boost telomeres.

1:15:58 And so we can set you back another year or two and you age another year and then we find something new that comes along that will set you back even further. So I think it’s a stepwise process, but I don’t think it’s unrealistic for anybody generally under the age of 55 to potentially see 150. 150. And you called it, what is that term you used about the quality of life, not longevity, but a health span? Health span, I love that term.

1:16:28 So that means that those last 50 years of my life, I’m not lying in a bed in a nursing home, just celebrating my 149th birthday and posting on Instagram, look how old I am. This is like healthy years, is what you’re talking about. Healthy years. Okay, that’s hard for me to believe. Again, I don’t see many hundred year olds that are living proof, but that’s because it’s too late for them.

1:16:48 Well, and you know, it’s the hundredth monkey. You know, once we get enough people that are truly believing this, we’re gonna start seeing it happen. And it’s one of those things that’s still in that realm of science fiction for most people. But the people that are running around in this industry, man, and there’s still some naysayers in the group, but there’s enough people that are optimistic about it that actually have some of the knowledge that it’s gonna happen.

1:17:20 I feel pretty confident. All right, well, I can be your guinea pig and you can get me to 150. How’s that sound? Right behind me. Okay, right behind you, right?

1:17:31 But I feel like I’m healthy enough, right? I haven’t damaged things too bad that we can keep this moment going. I think Aubrey de Grey talks about the longevity escape velocity, so you’ve got to stay above the certain line of health to take advantage of the coming technologies that will change that. Yeah, because you do have to have that line, right? Yeah, if you drop below that line, you’ve missed the escape velocity, you just can’t do it.

1:17:54 So under 55 and reasonable health, you might be able to figure out. I say that, but again, it’s all very general. Numbers mean nothing. Chronologic age means absolutely nothing. True.

1:18:04 And that makes so sense. It’s funny, I post my breakdancing videos on Instagram and on every single video, I get a I’m 25 years old and I can’t do that. Comment, you know, and I get all that. So it’s like people are seeing that and they’re like, oh wait a second, I’m younger and I can’t do these things. So what is age?

1:18:22 What does that mean? We did the Spartan race here in Austin recently and we had 25 of our coaches and clinicians and some of our clients actually competing in it with us and we just did it for fun. But it was interesting to see some of these younger people on the course that are impressed with what we were able to do in the Salmon Ladders and things like that and going across the rocker and you know it was like the exception they’re looking at you like you’re the exception and yet the world I run into this is not the exception this is the norm and I like it that way people in their 50s competing is what you’re saying yeah that kind of thing yeah how old are you 52 52 okay so for you you’re used to this but the kids see it and they’re like oh wow this is kind of neat it’s very inspiring for the young people too yeah I mean you see me into a rock climbing and they’re like hey he’s pretty good for an old man and I’m like I’m not an old man that’s right right and not my mind for sure and not my body what about stem cells we hear so much about stem cells it’s also a very general term they can reply to a lot of very specific cells right yeah we hear people going on a Panama for this stuff and there’s a lot of tell us what What should we know about these things?

1:19:43 You know, I have my own opinion on this, but I think we’re not quite where we think we are with stem cells yet. We just don’t really know as much as we really need to as far as what they’re capable of doing. Now, injecting into some joints and injured areas and things like that, I think they’re doing well. The IV stem cells, there’s been some complications with those and whether you use your own stem cells versus you use placental or umbilical derived stem cells that are donated, there’s differences in outcome with that and you can potentially have a bad reaction from those.

1:20:27 I’m just not, I’m not 100% sold on that and then after that study with the congestive heart failure and the stem cells and the data that was kind of flawed data on that kind of gave it a black eye. Didn’t hear about that was we kind of stepped back and said okay Let’s just wait and see what what pans out with this So of the biologics the stem cells are the ones I’m most leery about at the moment Like a peptide you feel comfortable with because it’s like this small piece of protein and has this reaction It’s not it’s common sense, right? It’s Generally recognized as safe. I mean you look at it and you say, you know, you could even overdose on some of these peptides and and the body will just say, oh, okay, there’s something happening that’s caused a surge in this, I’m gonna ignore it.

1:21:10 So, you know, it seems like that the peptides are a pretty good option. I’ve had guests on like Bruce Lipton talking about epigenetics. A lot of people talking about these things. What do you think of the talk and people like Bruce and, you know, Joe Dispenza talking about taking your mind and using it to express or not express, you know, genes and cancer genes in your body. It’s something that’s being talked about a lot, but these people aren’t medical doctors necessarily.

1:21:39 Yeah, I mean, I teach clinical application of epigenetics as a guest lecturer at Stanford every semester. There’s a lot of using of the term that’s not necessarily appropriate, using of the term of epigenetics. I mean, to say that everything we do can potentially change gene expression, that’s absolutely true. I mean, there’s aspects of it, but to attribute science behind it, we’re not quite there yet. I know that if I take fish oil, we know gene expressions.

1:22:11 These genes up-regulate, these genes down-regulate. If we exercise these changes, we have data on those. Now, saying that thought processing can change genes, not quite that direct, but if we have a lot of stressful thoughts, it’s going to activate hormone systems and that will definitely change gene expressions. But I think some of it was taken a little far into the non-scientific realm with some of the comments that have been attributed to epigenetics, and that’s why you have to be very cautious when using the term epigenetics, because it’s just kind of been adopted by a lot of different communities and not necessarily from the full scientific realm.

1:22:56 Yeah, I guess I mean, it’s like that word stem cell for a long time, which people threw it out and it was a big buzzword, but it was like all these different types of stem cells, all these different uses, and then just kind of throwing it into this big wave of excitement, but then you gotta dissect it to find out what’s really there. But you are a big believer of this, and you teach this, and this is the future. That’s right, and we have the science behind it.

1:23:19 I mean, there’s 16,000 peer-reviewed studies done last year on epigenetics. I mean, there’s 200 clinical trials currently under investigation in epigenetics. So, you know, physicians are some of the most skeptical of epigenetics, which surprised me. They had no idea, you know, I was talking at this one group of physicians about epigenetics and people said, you know, is this real science? I’m like, 16,000 peer-reviewed studies is pretty good science, in my opinion.

1:23:48 We have the science behind it, but again, I mean, most physicians are not staying relevant and up-to-date on a lot of the technology. I mean, there’s a few that are really cutting edge, but if they’re not putting the time into the educational piece, it’s gonna leave them behind. Do you think someday, when babies are born, they’ll have these epigenetic things run to where you just know it’ll be part of that birth certificate process? The data will be like the island.

1:24:19 You know, you pee into the urinal every morning and it assesses your vitamin need and your nutrient need. I think that kind of stuff is coming. It’s this data tracking technology. I mean, when I go out and run, I feel like I’m a cyborg. I’ve got my watch on, I’ve got my chest strap, I’ve got my wireless earbuds.

1:24:40 I’ve got my Humon Hex, which measures my tissue oxygenation on my thigh. I mean, you’re going out to run, but you’re tracking all this stuff and you’re getting great data. And once you start to learn how to use that data, I mean, it’s addicting, just like you found with wearing the watch at night for sleep. I mean, the first thing my wife and I do when we wake up in the morning, we’re like competing for our stress scores. What were you last night?

1:25:05 Oh, I was 11, I was eight. You know, I beat ya. We look at those kind of things, but we also pay attention to each other’s effects. So like, if I have a glass of wine, my stress score will go up 20 points for the next eight to 12 hours. So I know a glass of wine, even though I can convince myself that it’s healthy for me, I know from my data that it’s probably not.

1:25:28 So I kind of minimize the alcohol intake for sure. And since we are so subjective about our own selves, like to a fault, right? We’ll tell ourselves whatever narrative we want to justify the behavior, or sometimes reverse engineer the behavior. That’s why data is so important for an individual because it makes you honest, right? Well, you’ve got to have that independent interpretation, some objective feedback.

1:25:52 Because even when I’ll look at my stress level going up, I’ll try to justify it by something, and my wife will go, no, it was because of that. And I’m like, yeah, you’re right. You want to make it look, we have cognitive bias. I mean, that’s the nature of life for us. That’s just humans, yeah.

1:26:10 Well, if anybody wants to jump on board with this, again, it’s LondonReal.tv forward slash health. I’m gonna start getting, I think, all of my Life Accelerator students in my academy to do this when they join because just being aware of these numbers, I think that alone is enough to get people to start really thinking about their behaviors because we already have people doing movement and changing their diet and changing their mindset, but just to see something and to have someone independently saying, hey, look out for this, this, and this. I mean, even you telling me this stuff today is gonna start changing my behaviors because I know there’s some data out there, so this is super powerful stuff and I’m looking forward to seeing what you’re gonna do with me over the next few months.

1:26:47 I am too. No, it’s really exciting, and like a lot of people are watching me too, so I feel like the guinea pig in the glass case. Like I was last year for Iron Mind, I mean my whole life was just ripped out in front of everyone. I was interviewing my wife on camera, she was hating me because of the movie. I was like all this past addiction for me, it was like super shameful, but it all came out okay.

1:27:06 And it made you who you are. Yeah, it was a great result. Tell me a bit about you. What is something that you do every day that’s kind of non-negotiable, something that you learned that just makes you the best human. Well, one thing, prioritizing sleep.

1:27:23 I have not used an alarm in probably eight years. And I’ve regulated my schedule to the point where I don’t start my true work day, where I’m available until 10 AM. And I wake up at five, routinely, seven days a week. I’m out of bed between 4.45 and 5.15. That’s just my routine.

1:27:46 When are you going to sleep? 9.30, typically. Okay, all right. Sometimes 10, but sleep is a priority for me. And after years of being a surgeon with no sleep and a surgical resident, you just got none.

1:28:00 That industry basically ruins people because… It kills people. Right, it kills people. There was a rumor that it all came from Johns Hopkins who used to be addicted to cocaine, and then this whole like, I’m tougher than you, I can work more hours than you, pervaded the doctor industry. Oh yeah.

1:28:16 Is that true? Oh yeah, I mean the surgeons especially, surgeons were relentless with their berating of the surgical residents. I mean, they haven’t- They’re sleeping too much. It’s a superiority thing. I mean, you know, my wife always jokes that I had to get rid of my ego when I left surgery.

1:28:34 And to a degree, there’s a good thing. I mean, you’re a surgeon, He wanted a very confident surgeon working on you. And he better be a badass or think he’s a badass when he goes in there. It makes a difference, and they kind of breed that into you, but I saw a study recently they were looking at epigenetic age and they were looking at medical students, I think of it, or residents. It was residents they were looking at, and they accelerated aging that was occurring from the start to the end of residency, and even now, I mean, now they have these He’s like trying to make it more socially healthy for the rest.

1:29:09 So if you’re on for 12 hours, you have to have 12 hours off and all this. I mean, I can remember going in on a Friday morning at 5 a.m. and being on call in the trauma, on trauma call, I was second call, but you still got a little bit of sleep, not leaving until Monday evening. I mean, the day my first child was born, I had actually come home from a Friday to Monday shift, had dinner and I was exhausted and my wife said, don’t go to sleep. I was like, oh my God, okay.

1:29:47 So, I mean, that was the routine back then. So I can see why the aging process is so impactful. So dangerous too, right? I mean, I saw many mistakes from sleep deprivation in residence. Okay, so you know, don’t use alarms.

1:30:02 You go to sleep nine, 30, 10, and then you wake up naturally at five. At five, and typically, you know, those first two hours of the day, I’ll typically get on the computer and start reading. Sometimes my wife and I, most days, we actually go for a walk. So we live right on the river in Austin, so we just walk outside and we do a three or four mile walk, come back in, finish up what I was doing. And then try to get exercise in before before 10 a.m.

1:30:31 But I also have a very strict schedule where 11 3 to 1 nothing can be scheduled in that So I have 10 to 11 30 for my first part of the day to get some stuff done 11 to 1 30 I’m gonna have a lunch. I’m gonna work out you know if I haven’t worked out in the morning, that’s my my workout time and All of my team know those are untouchable times for me unless it’s an absolute emergency And then from one o’clock on it’s wide open so you know and as an entrepreneur You know you I work seven days a week, and you just don’t have breaks But my days are structured like that so my weekdays are actually probably better than my weekends because I actually have that structure, too Interesting yeah, I go train here every day pretty much at 1 30 and it’s just not negotiable And everyone kind of knows my routine now, and I just have to do it It’s my way to shut off and reset and I look forward to it. It’s just yeah, I don’t know for me now It’s where probably my brain gets to turn off. I get to focus on something maybe get into some flow Maybe not but it’s just it’s like a non negotiable when I don’t do it I feel it’s and I think that’s what makes a difference for people like you and I is that when we Have that non negotiable piece of it and set that in stone and say Not touchable. Yeah, that makes a huge difference good advice for someone who’s watching If I were to ask a bunch of your friends and say what is Daniel’s superpower,

1:31:57 What would they tell me that it is? How are you able to do all this stuff and build this organization? Because I’m sure a lot of people want to do this, but what would they say is your superpower? How are you able to do that? I would say it’s probably my ability to handle stress.

1:32:15 I look at stress as a real challenge. You know, it’s an opportunity of growth. I don’t get irritated, I don’t get stressed over things. I mean, some people will be stressing out over something. I’m like, it’s not that big of a deal here, just do this.

1:32:33 Always been the case? No. Okay. No, when I was a surgeon, it was very different. Yelled a lot.

1:32:38 Yeah. Because that was the culture. Yeah, I mean, you had expectations and if people didn’t meet those expectations, you let them know. I don’t, I’m not like that though. I’m very, very calm and just don’t have any negative stress response.

1:32:56 I mean, you know, it’s one of the things I can look at and, you know, my wife runs the psychophysiologic performance test on me and my stress response to stressors, I can elevate the stress when I need to, but I can bring it straight back down into baseline. And I think that truly is a superpower. You know, I always say my wife, her nickname for me is Batman. I love Batman because Batman is a superhero that wasn’t born with any special gifts, but through training and technology, he’s become superhuman.

1:33:29 I was like, oh, that’s perfect. And she was calling me that for years, but now it’s appropriate. That’s nice. I’d love to test myself and see how I do with this stress and then getting back to baseline. When I worked in banking and in trading, I found, I think I learned a behavior of how to handle a really stressful, time-sensitive environment where you’ve got a big potential gaping wound of a problem, you got markets moving, you got people yelling, you got people that are emotional, and it’s like, okay, we need to make the right decision in the next 90 seconds and the wrong decision could be a real bad thing.

1:34:04 Now, maybe not as bad as someone on an operating table, but it was just like, it was interesting to see it work out and to realize that being able to be calm but alert made all the difference. I got really conditioned to doing that to where nowadays when there’s a problem, it never feels like the same magnitude as that. You’ll probably feel that way too. After the operating room, I’m sure. Yeah, and truly, I actually have a better stress response now than I think I had then.

1:34:32 What does this whole business look like 10 years from now if it’s what you want it to be? What are people getting from this? What are you doing with people? What kind of successes are you seeing? How big is it, what’s your vision?

1:34:47 The vision is that we have created a new world view. The human system doesn’t have these definable limits, that this is all possible. Get people of that mindset, because when that world view changes, that’s when advances are going to accelerate. And for us, we have our training academy, we have our genetic portion, We have our medical center and I think they all interact. So what we envision is We’ve currently got Austin, Texas Asheville, North Carolina, Sarasota getting ready to open London and possibly Dubai. I See these medical centers as hubs throughout the world Supporting the coaches that are around that because one of the one of the issues that people have is 80% of people that go to a physician won’t tell the physician about the health coach or the the acupuncturist or the chiropractor that they’re seeing, they won’t share that with them.

1:35:46 And I don’t know, I mean, they think that they’re gonna be discounted for what they’re doing. And they probably will be. With a lot of physicians, they might be. But in our academy, we have, I mean, we have coaches from every walk of life. And they all interact on this group coach’s platform that we have.

1:36:08 And they share equally all their knowledge from all these different areas. So our coaches are the most well-rounded coaches you’ll ever encounter. And if they don’t have the knowledge, they come on and say, hey, I’ve got this patient that’s got this, what do you guys think? And you know, they’re getting input from physicians in every specialty, chiropractors, natural paths, psychologists, pharmacists, that are all these coaches that are all contributing equally.

1:36:29 And with this network, we’ll have coaches out there working with clients that will feel comfortable referring and having continuity of the philosophy and who they’re referring to when they refer up to the medical centers. And so I see these little hubs everywhere around the world with these larger rings of the coaching network around them. Okay, what scares you? Nothing, really, absolutely nothing. And why is that?

1:36:58 You know, I look at life as we’re here to experience. And the goal is to take this experience to its greatest level. What can we achieve? What can we do? And so every day is like a discovery of something new that we can create.

1:37:20 That perspective on life has been very different for me in looking at it as the experience. Everybody needs a purpose, and I don’t have a need to have a purpose. My goal with building this is to have fun with it and to create something. It’s not a purpose that I’m driven to do it, it’s just to take the experience to its fullest extent. What can I create in this life that I have and have fun with it?

1:37:50 It’s exciting. What’s that phone call you wanna get from someone? Maybe from me, in six months time, and I say, doctor, this just happened, or what’s that call that you’ve gotten in the last year from one of your clients where you’re just like, wow, I love what I do? Oh, you know, especially with some of the entrepreneurs I have, they love posting their stuff online. You know, and I had this one entrepreneur from Canada who had broken the 10% mark on his body composition.

1:38:20 I mean, this guy, he gained 25 pounds of muscle and lost 25 pounds of fat, so his weight didn’t change in the course of 18 months of working with us. And he got his black belt in jiu-jitsu, He had another child, his business 10X’d over the course of it. And you can watch videos of him prior to the time he worked with us and then after 18 months and the confidence level is enormous. But when he texted me, his DEXA scan and he posted online. I mean, he posted this thing and just was raving about his outcome with us.

1:38:54 That is when we see people achieve potentials that they they imagined and they thought yeah that’s possible and then they hit that because at that point when they hit that they know there’s nothing it that they can’t achieve at that point right just getting warmed up at that point yeah and and that’s what he said to me he said what’s next right I’m like I love this that’s my favorite term is what’s next what’s next yeah it was funny we had I had David Goggins in here last week, and he’s all about getting that body to a level where the brain just expands and just says, oh, wow, I didn’t know I could do this. And then once it does that, it’s like, okay, what else can I do? And it’s all of these different.

1:39:43 I mean, we talk about consciousness and enlightenment and everything like this. This is enlightenment when you come to that realization. Powerful, isn’t it? Yeah. And it can be done through the body, right?

1:39:55 You’ve heard this expression, the body is the mind. Like, what do you think about when you think about those things? Is it all one system that a lot of times we separate? You know, that gets into the religious aspect of it. But like I said, I see the body and mind as the, you know, it is the vehicle of consciousness.

1:40:13 It is carrying our consciousness. And what we do with it is going to definitely impact every aspect of our expression of consciousness. Yeah, yeah, the driving around in the Pinto gets old after a while. Yeah affects everything that you do and everything you see You can feel every bump on the road or you could be the Ferrari. I absolutely want the Ferrari You and a lot of people what keeps you awake at night?

1:40:39 Absolutely. Nothing. Nothing. I am the best sleeper. I mean routinely I can I can fall asleep in You know 10 minutes of my head hitting the pillow and I sleep soundly through the night Very little can even disturb me. Once I go to sleep, it is out like a light until Until about 5 a.m. And I just spontaneously wake up and it’s as how Elrod says it’s like Christmas morning, you know, I’m I Get excited about my cup of coffee You know, I’m like coffee time, you know, I am a Firmatic to large volumes of coffee in the course of a day Okay And nothing else is on your mind besides nothing when I wake up in the morning all is on my mind is is coffee.

1:41:23 Coffee and ready to go, right? Yeah, I mean it truly is like Christmas morning. I’m jumping out of bed and excited to start the day. Wow, I’m just trying to make sure, but I think we covered a lot of this stuff, right? Is there anything I missed?

1:41:37 We went through a lot of stuff. We went through a lot of stuff there. I always ask my guests some questions at the end. I’m gonna ask you right now, if I could give you a magic phone and you could ring up the 20-year-old Daniel and give that young man some advice, what would you tell him based on everything you know now? I wouldn’t tell him anything.

1:41:54 You know, I wouldn’t want to change that trajectory because I really like where I am. I like what I’ve become. Plenty of mistakes along the way. But those mistakes were really what helped get me to this point. The following success secrets are only available inside the London Real Tribe, where you get exclusive access and insights from our high performance guests on wealth creation, productivity, leadership, morning routines, health, and well-being.

1:42:26 To join our tribe community, go to londonreal.tv forward slash tribe. Now, let’s continue with the show. I agree. I mean, I don’t think today I would be, so I haven’t had a drink in 18 months. I don’t smoke anymore. I train every day. I really work on my sleep. I mean like, I don’t think I would do that stuff if I hadn’t have gone the other route to where I, you know, I didn’t want to wake up hungover again.

1:42:51 I didn’t want to be dependent on a substance to make me happy. I think all that got so old To where I hated myself for all that stuff where now like I guard my sleep time my training time My meditation like like a soldier like nobody fucks with that time Yeah, cuz I know I could turn into that guy again So I knew what you mean, you know it was those lessons taught me to be really grateful for this and also to cherish it and make sure that I that tomorrow is is another great day or a better day. And that even may not value it as much if you had never gone through it.

1:43:26 Yeah, on that same note, what’s the best advice you’ve ever received? Again, it could have come from another doctor or something you heard someone say or is there something along the way or a parent? You have no need for the good opinion of others. Was probably one of the best pieces of advice and I’m not even sure who gave it to me or if I read it somewhere. but doing things for the purpose of getting approval.

1:43:55 Once you get beyond that point where you need that, I think that’s an enlightening moment for people and it was for me. Yeah, very much so. Last question, to that 20-year-old that’s watching us, advice to them, and again, I watched some of your older lectures on YouTube. Now, of course, people will have this wonderful piece of content, but you were saying that it’s one thing when it’s a guy your age or my age talking about this stuff, but a lot of times, the younger kids, they’re not thinking about their body when they’re young.

1:44:21 So what is your advice to a 20 year old who’s out there who can back squat 400 pounds and drink a 12 pack and sleep on two hours and they’re like, I don’t need to listen to you guys. What do you tell them about their body? Well, I have to say, you know, the youthful reproductive male has such resiliency in the system that they can probably get away with a lot of that stuff. I mean, heck, I got away with a whole lot of stuff when I was that age that would probably kill me right now if I did them.

1:44:51 So I think, you know, I say youth is wasted on the young because you just don’t know. You’ve got this, I mean, truly optimized system that you don’t know how to use. Then when we get old enough to understand that the system’s breaking down and we’ve got to kind of do the corrections. You know, I think with the youthful group, success not only from a bodily status of aging and success in life comes down to certain disciplines that I think are important and sleep would be the one thing that I would prioritize.

1:45:32 I mean, if you can change one thing in your life, it would be get sleep. It has such profound effects on every aspect of human performance. Powerful advice, I had a guy named Matthew Walker in here recently, wrote a whole book about that and did some consults for Google, but he was literally in that chair saying, you know, your lack of sleep is killing you. And everyone’s like, yeah, yeah, yeah, and he’s like, no, no, no, no, it’s literally killing you. And it’s just this weird thing that we’re happy to marginalize as humans, and yet we’ll stay away from like radioactivity and all these other things.

1:46:05 But yeah, it’s great to hear you say that because I agree. Well, and see, I wouldn’t even say it kills you. I would say, you know, you can leverage sleep to upgrade performance. Right. Right, so take it the other way.

1:46:17 Yeah. Right. And become super optimal, so. Right. Awesome, I’m super excited about this partnership that we have, and for people that are interested again, just get that basic epigenetics test with the consultant and everything.

1:46:29 We’ve got that special site, LondonReal.tv forward slash health, it’s a discounted price if you wanna start there. And then from there, they can choose if they wanna go to another levels. I think we’re gonna be going to the next level with me and seeing what we can do. I already thought I was crushing it, but now we’ll see what can happen next. And I’m really excited about a lot of these like peptides and this other stuff.

1:46:46 And I’ll also be honest, it’s nice that you’re in America and you’re in Austin, because I feel like you guys are years ahead of what’s happening over here in London. And so when you guys, when I first met you, you’re telling about this stuff and it’s just like, what? It does sound like the limitless movie, but it’s also not. And I’ve had a little experience with some of the stuff to just realize, Wow, if you’re really in the know, you can be ahead of the curve.

1:47:10 You can be the one percenters of people that are ahead of the curve and that’s gonna make a profound difference in where your life is in the next 50 years. Are you there? Is your family there? What’s gonna happen? Exactly.

1:47:22 It’s exciting stuff, so thanks for that. I appreciate it. Thanks for giving me my readings as well. And yeah, looking forward to what we do in the future. That’s gonna be fun.

1:47:31 All right, great talking to you. Thanks so much.